The MicroRESP system was designed as a small scale bioreactor to study the activity of the soil microbial community in terms of the amount of CO2 respired per time, which is quantified by pH sensitive dyes in 96 well microplates using a Biotek Epoch 2 microplate reader. Each microplate can have a variety of naturally occurring substrates added to investigate the physiology of the soil microbial community, or deleterious substances.